The Catalysis and Chiral Technologies group of
Johnson Matthey is
pleased to present our monthly edition of Catalysis
Forum. Our goal is
to provide a convenient means for you to receive
updates on our
latest developments in catalysis.
Request literature:
Johnson Matthey is pleased to announce the addition of
Trichickenfootphos (TCFP) to its chiral ligand offering.
TCFP offers a new dimension to the Johnson Matthey
portfolio as it
represents our first P-chiral ligand that is
both small and highly
electron rich.
This combination gives TCFP unique properties that
allow it to
perform rhodium based catalysis on a range
of prochiral substrates
where more typical ligands fail.
The rhodium catalysts prepared from the ligand are
excellent for the asymmetric reduction of:
- enamides
- ketones
- unsaturated acids
The advantage of the small molecular weight and the
very electron rich
phosphines means excellent
turnover numbers are achieved on a
weight/weight
basis and the stereochemical message of the P-chiral
centre close to the metal allows very high asymmetric
induction.
Johnson Matthey has successfully scaled TCFP to multi-kilo production and it is
now available through our global sales outlets.
Contact us for more information at: JM Catalysts Inquires
